Sixteen-year-old Deedee runs away from Louisiana to live with her half-brother Bill, an English teacher who happens to be gay. Lucia, Bill's sexually-repressed best friend, distrusts her. These suspicions are confirmed when Deedee lures Bill's boyfriend into bed and talks him into stealing $10,000 from Bill and running away with her to Los Angeles. To make matters worse for Bill, his bitter ex-lover frames him for sexual harassment, causing a scandal in their quiet town. This forces him and Lucia to go on a wild chase in search of Matt and Deedee in order to clear his name. They are joined by Sheriff Carl Tippett, a friend, who begins to fall in love with Lucia. A black comedy about what people must go through in order to find "the opposite of sex" - lasting, committed, and loving relationships.