Ten volumes of the 11-volume "Encyclopaedia of Afghani Jihad" found at the one-eyed, hook-handed imam's west London home advised hitting landmarks like London's Big Ben, the Statue of Liberty or the Eiffel Tower, the jury was told.
The book, written in Arabic sometime between 1989 and 1999, also contained information on how to make bombs and booby traps, manufacture weapons and engage in secret communication.
But although it was concerned with the Afghan Mujahideen fighting the occupying Russian forces at the time, it also talked of an "external pressures" unit which would operate abroad, prosecutor David Perry said.
Egyptian-born Hamza, a British citizen by marriage who preached at Finsbury Park mosque in north London, faces a total of 15 charges, including nine of "soliciting to murder".
Racial hatred
Four of the charges concern using language aimed at stirring up racial hatred while another relates to the encyclopaedia, which it is alleged contained information "likely to be useful to a person committing or preparing an act of terrorism".
Opening the case, Mr Perry told the court the book said plans "should be laid out" to target buildings such as skyscrapers, ports, airports, nuclear plants and football stadiums.
The book, dedicated to "Abu Abdullah Osama bin Laden" for "carrying out 'jihad' in Afghanistan and who is still, to this date, inciting 'jihad'" also talked of attacking large groups of people at Christmas.
"This is a blueprint, a manual for terrorism which echoes the things which feature in the defendant's speeches," said Mr Perry.
The court was told Hamza preached "murder and hatred" during his sermons and lectures, many of which were recorded on audio and video tapes found at his home.
In them, the prosecution said he called on his followers to carry out their "religious duty" to Allah and kill Jews, "infidels" and lapsed Muslims as part of the fight against enemies of Islam.
Legitimate targets for his violent form of "jihad", literally "struggle" in Arabic, included what he called "apostates" or lapsed Muslims and the leaders of a number of Arab countries who were "too friendly" with the West.
The struggle would go towards establishing a "world caliphate" or Muslim government under Sharia law, even at the White House in Washington.
Preached intolerance
In one address, Hamza allegedly said Jews, who he believed "controlled" the West, should be "removed from the Earth".
"You would think... that in his position of responsibility, that in his position as a spiritual leader and civic leader, he would be preaching tolerance, mutual co-existence and responsibility regardless of race, colour or creed," Mr Perry said.
"In fact he preached the opposite. He preached intolerance, bigotry and hatred, in particular against Jews as a racial group and a religious body.
"In the course of one of the lectures or sermons, he accuses the Jews of being blasphemers, traitors and dirty," the jury was told.
"This, because of their treachery, because of their blasphemy, was why Hitler was sent into the world."
Hamza, who denies the charges, did not answer questions after his arrest on May 27, 2004 but instead gave a statement claiming Islam was being placed on trial and he had been subjected to a witch hunt by the media, the court heard.
He denied hating Jews or Christians and said the encyclopaedia had been a gift which he had never read. The trial is expected to last about three weeks.