The three office buildings, designed by architects Norman Foster, Richard Rogers and Fumihiko Maki, will complete the plans for a new World Trade Centre.
The complex already includes the 541 metre "Freedom Tower" and a memorial to the nearly 3,000 victims of the attacks.
City officials hope the new office buildings will be completed with all of the World Trade Centre reconstruction by 2012.
Tower 2 has been designed by British architect Foster and will stand 382 meters tall with 78 floors.
"The dramatic height of the tower celebrates the spirit that has historically driving Manhattan to build tall, and the diamond-shaped top will be a crowning landmark on the city's skyline," Foster said.
Rogers said that his 352-metre Tower 3 "responds both to the architectural and social context of the area."
The lobby will have a three-story picture window onto the World Trade Centre memorial.
Tower 4, designed by Maki at 288 metres tall, completes the site with a minimalist design.
"The new towers will be a magnificent addition to the rebirth of Lower
Manhattan," said Mayor Michael Bloomberg.
He said that an economic boom would come to the area with the rebuilding.
"The new skyline that will be created will be worthy of our new 21st century downtown, restoring the splendor of our city's historic birthplace."