The Churches Advertising Network (CAN) will run the poster, which shows a glass with the words "Where will you find him?" as part of their campaign to boost attendance in the run-up to Christmas.
"The message is subtle but simple -- where is God in all the boozing at Christmas?" said CAN chairman Francis Goodwin, whose group is made up of Christians of all denominations working the British media and advertising.
"For many, Christmas is just drinking and partying and God is excluded, yet many young people are interested in finding deeper meaning and exploring faith."
The poster is also a nod to the occasional discoveries of holy images in everyday objects, from the face of Jesus in a frying pan, toast or fish finger, his mother Mary on a toasted cheese sandwich and even Mother Teresa in a sticky bun.
Previous advertising campaigns from CAN have included a poster depicting Jesus as the revolutionary leader Che Guevara and one suggesting Mary was having a "bad hair day" when she discovered she was pregnant.