









Immortal screens Sunday October 14, 2012 at 8:30pm on SBS ONE.
Watch
the RiAus-Immortal event
Could scientists really have discovered the
secret to endless youth?
Is there really such a thing as an immortalising enzyme, a chemical
catalyst that can keep cells young forever?
A team of scientists, lead by the remarkable Australian-born Professor
Elizabeth Blackburn, believe the answer to be yes.
In 2009, Elizabeth and her team’s discovery of an enzyme deep in the DNA
of a single-celled pond creature, the so-called 'immortalising enzyme',
was awarded the Nobel Prize for Physiology or Medicine.
Now, this remarkable enzyme is being harnessed. The molecular clock it
controls - the countdown to death in each cell - can be tested, measured
and, in some cases, it can even be stopped. Amazingly, middle-aged human
cells have been replenished and rejuvenated by triggering this enzyme,
becoming, in effect, young again. Many believe that the cure for
ageing, has now arrived.
But there is a dark side to this incredible find.
The immortalising enzyme is a complex biological riddle, with a
paradox at its core. This same enzyme that fuels life, also fuels
cancer. Cancer it seems, is the true immortal. It has the ability to
replicate endlessly, ignoring instructions to die. And cancer cells have
hyperactive levels of this same enzyme. So the key to endless life, is
also the key to cancer's deadly success.
The challenge is now on to find a balance between the power to extend
life, and the ability to destroy it.
Featuring Nobel Prize winners and experts in ageing, personal stories
and provocative old films, Immortal reveals the inner workings of this
biological paradox and its remarkable impact on ageing, disease and
cancer. We also discover the role of stress and lifestyle in the ageing
process and what steps we can all take, right now, to protect our
precious genetic material. For today, around the globe, brilliant minds
are busy harnessing this cellular fountain of youth to help us all
live longer and healthier lives.
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