The Dutch powerhouse timed her sprint perfectly off the back of a strong lead out by team mate Janicke Gunvaldsen to beat the large bunch home at the end of a dozen 5.5km circuits.
“At first I thought I was too far back at the last corner, but then I started to pass a lot of riders and I knew I could do it,” Wild said.
“It was all down to really good teamwork. We know what to do, so that makes my job easy.”
“It is always good to win and it was a nice fast race. Racing on these big famous streets is really cool. I had done a lot of training and I was ready for it. But you can never tell what’s going to happen in a sprint," she said.
With the Prudential RideLondon Classique offering an equal €100,000 prize money pool to the men's race, Wild went home €25,000 richer.
“Winning is always good but especially with this big prize,” she said.
Wild's fellow compatriot Lucinda Brand (Rabo-Liv) took the Queen of the Sprints title, with Australia's Sarah Roy (Orica-AIS) finishing second.
“We are used to this kind of race in the Netherlands, and we love it,” said Brand.
The race was characterised by numerous attacks off the front, including a spirited effort by Australia's Jessica Allen. With four laps remaining, the new Orica-AIS signing, attacked and held a 10 second lead until she was caught with just two circuits to race.