Dideriksen (Boels Dolmans) ran out to a clear victory ahead of Lotta Lepisto (Cervélo-Bigla) and Marianne Vos (WaowDeals).
"We knew everyone was going to be a little tired coming into the sprint but with about 30kms to go we decided that it’d be me we’d ride for," Dideriksen said.
"The girls did an amazing lead-out and, you have to be patient in the end but still go before everyone else comes from behind. So I’m really happy I could pull it off."
The victory came after a trio of breakaway riders, including Cecilie Uttrup Ludwig (Cervélo-Bigla), Audrey Cordon Ragot (Wiggle HIGH5) and Charlotte Becker (Hitec Products-BIRK Sport) were caught with seven kilometres remaining left in the 130km stage from Wychavon District to Worcester.
Vos’s time bonus for third place brought her one second closer to overall leader Coryn Rivera (Sunweb), who retains the overall lead for a third day.
"There was a really good stretch of cross tailwind and the girls did a great job and strung the field out with Boels Dolmans," Rivera said. "It made the race hard and it was all about controlling the break from that point on."
Rivera now sits 14 seconds ahead of Vos, with her WaowDeals team-mate Dani Rowe third overall at 22 seconds. Four other riders are within 30 seconds of the lead going into a tough final stage.
"Tomorrow is going to be a hard day," Rivera said. "Lots of climbers and Boels and Canyon-SRAM, I’m anticipating, will make it difficult.
"As long as we stay together, there is a long way to the finish line after that last climb. Teamwork will be the most important thing tomorrow."
The OVO Energy Women’s Tour ends with Stage 5 covering 122 kilometres from Dolgellau to Colwyn Bay.