The actor, there to honor Shep Gordon, was barely able to stand up straight as he stammered through his speech to award Gordon, the subject of Mike Myers' new documentary, "Supermensch: The Legend of Shep Gordon."
"It's just one of those nights," he said before CBS appeared to cut him off.
Backstage, Myers called Depp's expletive-laden introduction "very rock n' roll."
Twitter users, meanwhile, thought the actor was simply "wasted."
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