The movie is a coming-of-age story that follows 14-year-old Charlie Bucktin over the summer of 1965, as he gets caught up in the aftermath of a murder and small-town racism.
Levi Miller (upcoming Blue Dog) will play Charlie, and Aaron McGrath (Around the Block, Redfern Now, Glitch) is Jasper Jones. Angourie Rice (These Final Hours) has been cast as Charlie's love interest Eliza Wishart.
"The kids are the heart of the film and they are all brilliantly talented,” Rachel Perkins said in a statement.
The screenplay has been written by Shaun Grant (Snowtown) and Craig Silvey, and filming will begin in the South West region of Western Australia in October.