Concha Velasco studied dancing and became an actress in a revue with Celia Gámez. In 1954 she made her film debut  with roles in several minor films.

At the end of the regime of dictator Francisco Franco she worked with director José Luis Sáenz de Heredia, among others, in higher-quality films, such as Torment (1974) and Pim, Pam, Pum... Fire!  (1975), which gave her a better reputation. After this her films were more successful, such as "Teresa de Jesús" (1984) in which she played Santa Teresa de Ávila.