Originating in China and spreading on the battlegrounds of the World War I, Spanish flu made its way across western Europe with the return of soldiers in 1918. It had a devastating effect on a world recovering from war.
It killed an estimated 50 to 100 million people worldwide, far exceeding the total losses of World War I (18 million).
In Australia, the death toll was 15,000 which was significant for a population of only five million.
Source: NATIONAL MUSEUM OF HEALTH AND ME
Infectious diseases expert from the Centre for International Security Studies, Associate Professor Adam Kamradt-Scott, said much like today, Australia implemented a quarantine period for international arrivals.
“The virus entered Australia in 1919 when a ship broke the quarantine period by just one day in Melbourne,” he said.
“The prime minister at the time was in Western Australia and the West Australians were concerned about the arrival of the disease from the east so they rolled boulders over train tracks."
Source: AUSTRALIAN WAR MEMORIAL
Professor Kamradt-Scott said the Spanish flu was particularly devastating in Pacific Island nations where infection rates reached as much as 50 per cent with fatality rates as high as 25 per cent.
Arising from a genetic reassortment of a bird virus, Asian flu got its name from its rapid spread on the continent.
The illness was relatively mild compared to the Spanish flu and there were fewer deaths worldwide (two million).
Professor Kamradt-Scott said the Asian flu pandemic demonstrated how vaccines were the cornerstone of pandemic preparedness.
Source: Chicago Tribune/TNS/Sipa USA
“Australia was one of the countries that implemented a vaccine program and it was part of our experience with the 1957 Asian flu that helped demonstrate the effectiveness of influenza vaccines.”
Hong Kong flu
About 10 years later another pandemic swept across the globe.
Hong Kong Flu mainly affected the elderly and spread between 1968 and 1970.
It was estimated to be the cause of one million deaths worldwide.
HIV/AIDs is the longest pandemic and the only one to not be a respiratory illness.
At its peak in the late 1990s HIV/AIDs killed about 1,000 people a year in Australia.
Associate Professor at the School of Public Health and Community Medicine, Dr James Wood, said as a sexually transmitted disease the level of person-to-person spread of HIV/AIDs was limited, compared to respiratory pandemics.
“HIV on a personal basis was worse, but it happened over a long time so you would get HIV and then develop AIDS without treatment between two and 10 years after your infection,” Dr Wood said.
“HIV being a slower infection gave researchers and drug companies time to develop treatments that would work.
“Unfortunately, for a flu pandemic or a coronavirus one we don’t have time to develop new responses,” he said.
Since its peak, HIV/AIDS has tapered off and in 2017 the Australian Federation of AIDs Organizations announced it was no longer a public health issue. This is mainly due to the development of preventative medication and increased education and awareness programs.
There are still around 28,000 people living with HIV/AIDS in Australia.
The most recent and mildest pandemic was in 2009.
Swine flu originated out of a small region in central Mexico in April 2009.
It quickly spread to the rest of the world and in June of that year the World Health Organization declared it a pandemic.
The first Australian case appeared in Queensland in May 2009. There were 37, 636 cases in Australia including 191 associated deaths.
Dr Wood said it was worse in pregnant women and the Indigenous population and it was never defeated, rather it became one of Australia's regular flu strains.
“The 2009 pandemic virus essentially knocked out one of the two influenza strains we usually get during flu season.
“And we now get it circulating every year, sometimes it's the main strain and sometimes it's not,” he said.
It was the second wave of the H1N1 virus, the first of which was the Spanish flu.
Swine flu infected 700-1400 million people globally - roughly 11-21 per cent of the global population.
It killed between 150,00 and 575,000 people, a much lower fatality rate than its cousin, Spanish flu.