The Melbourne-founded International Campaign to Abolish Nuclear Weapons will accept the Nobel Prize in Norway on Sunday.
It started with a handful of people in Melbourne a decade ago: now an international anti-nuclear weapons group has won a Nobel Peace Prize.
The International Campaign to Abolish Nuclear Weapons (ICAN) is the first Australian Nobel Laureate for peace and will accept the prestigious award in Norway on Sunday.
"These weapons are at the root of everything that is insecure about the world," founding member Dimity Hawkins told reporters in Melbourne on Sunday.
"At the time of the launch (in 2007) things were going backwards in terms of disarmament diplomacy and we needed to step it up."
There are 15,000 nuclear weapons in the world now, down from 30,000 when the ICAN campaign started.
Karina and Rose Lester, daughters of the late Yankunytjatjara Elder Yami Lester who went blind after British nuclear testing in South Australia in the 1950s, said the recognition was emotional for their community.
Karina also delivered an indigenous statement to the UN treaty negotiations earlier this year and said ICAN was an opportunity for her community to be heard.
"The British government thought that our country was barren and nobody was out there," Karina told reporters.
"What people fail to understand is that we're suffering today from this and we haven't been compensated either," Rose said.
A large focus for the group now is to get Australia to sign on with the prohibition treaty, with the country currently "on our own in our region", ICAN chair Richard Tanter said.
Australia seemed to be refusing to sign the treaty out of loyalty to the United States, he said.
Prof Tanter said with the threat of nuclear war between North Korea and the US, the world has two options, get more nuclear weapons or abolish the bomb.
"We know where the first path leads," he said. "The only path forward is prohibiting the bomb then abolishing it."
Leading Australian health and human rights campaigners are in Oslo for the ceremony, including Kokatha South Australian nuclear test survivor Sue Coleman-Haseldine and ICAN's founding chairman Tilman Ruff.
Hiroshima survivor Setsuko Thurlow, who was 13 when the Japanese city was bombed, will accept the award with ICAN's executive director Beatrice Fihn.
ICAN is now headquartered in Geneva, and describes itself as a coalition of non-governmental organisations in more than 100 countries.
It was awarded the Nobel Peace Prize in October for its work on the Treaty on the United Nations Prohibition of Nuclear Weapons, adopted by 122 countries in July.
The acceptance ceremony will be broadcast live at Melbourne Town Hall on Sunday night, where federal Greens leader Richard Di Natale and Karina and Rose Lester will speak.