"We are a $2.5 billion industry, we employ a lot of people – this is going to have a significant impact," Ms Richardson said.
"We're looking at a financial impact of hundreds of millions of dollars … and that would be a conservative estimate."
She stressed that for every cancelled rock concert or theatre event, there is a major "flow-on".
"There are a lot of moving parts with a show … There are the performers, there's the crew, there are many people involved in shows, some of which cost millions of dollars to put together."
'It's a substantial hit to our business'
Tasmania resident Chris Veevers is one of the thousands of Australians working in the music and arts industry.
Mr Veevers is a director at VJAM, a company that provides audio, lighting and staging services to festivals and events, including Dark Mofo.
Source: Facebook - Dark Mofo
"I had a meeting in Hobart with [organisers] MONA yesterday and they were gutted they had to pull the pin on it. They certainly understand the economic ramifications," Mr Veevers told SBS News.
"MONA is one of our largest customers … So it's a substantial hit to our business."
Mr Veevers said 15-20 of his staff were set to work over the two-week festival, in addition to a team of extra contractors.
And he said with the outbreak worsening, it looks like a grim few months ahead for the company.
"The issue is just about everything we do is based around congregations of people," he said.
"And I can't see it getting better any time soon."
Calls for more government action
Live Performance Australia's Ms Richardson said the government needed to step in and help prop up the music and arts sector at this time.
"We're particularly vulnerable and we're very concerned that many of the businesses – commercial and subsidised – won't see this through … We're looking at support from the federal government to survive," she said.
"We are calling on the government to provide financial support to our industry now to ensure that we are able to manage our way through this and ensure that we've got our businesses intact when we come out the other end."
On Thursday, Prime Minister Scott Morrison outlined a $17.6 billion economic plan to deal with the outbreak.
It included a one-off, tax-free $750 cheque for 6.5 million welfare recipients and pensioners as well as payments for eligible small and medium businesses.
Asked about the plan, Ms Richardson said, "our industry needs targeted assistance right now".
SBS News asked Arts Minister Paul Fletcher how the music and arts sector was directly being supported through the outbreak.
"The government is aware that the COVID-19 outbreak is causing wide-ranging impacts on all sectors across Australia," a spokesperson for the minister said in a statement.
The spokesperson said the $17.6 billion economic plan "will benefit around 690,000 businesses employing around 7.8 million people including those eligible in the arts sector".
"[And] I encourage the arts sector to continue monitoring advice from health and government authorities in planning their events."
Workers already 'at the economic margins'
The Media, Entertainment and Arts Alliance (MEAA) has also voiced concern that the government is not doing enough for the music and arts sector at this time.
A MEAA spokesperson told SBS News on Thursday, "this will be challenging for all workers in the sector".
"Many performers, crew and front of house staff are already working at the economic margins as a result of intermittent work and relatively low levels of income security and limited if any access to paid leave entitlements," the spokesperson said.
"It is extremely disappointing that the federal government announcement today failed to adopt the union movement's call for a further two weeks leave to be made available to employees and that equivalent entitlements be extended to individual contractors who are impacted by the virus."
Mr Morrison said on Thursday individual contractors and casual employees impacted by coronavirus can access a sickness allowance via Centrelink and that the one-week waiting time for this benefit will be waived.
There have been at least 128 cases of COVID-19 in Australia, with three deaths and at least 21 people recovered.