The 36-year-old who filed a since-settled lawsuit against Epstein's ex-girlfriend British socialite Ghislaine Maxwell, says she's grateful he will never harm anyone again, but is angry there will be no chance he answers for his conduct.
Ms Giuffre told The New York Times that her husband woke her up early in Australia to share the news that the wealthy financier died on Saturday morning in an apparent suicide.
Ms Giuffre said "We've worked so hard to get here, and he stole that from us, too."
Ms Giuffre, alleged in a 2016 deposition in the court filings that Epstein and Ms Maxwell groomed her to become a "sex slave" for him and his circle of cohorts, when she was 16.
She said she first met Ms Maxwell in 2000 while working at Donald Trump's Mar-a-Lago resort in Florida.
Epstein's death came hours after the release of 2,000 pages of court documents, part of a related lawsuit, that revealed allegations that Epstein and Ms Maxwell, ordered her to have sex with powerful men.
The records contain graphic allegations against Epstein who pleaded not guilty to sex trafficking charges.
The documents, for the first time, reveal the names of the men who Ms Giuffre alleges Ms Maxwell and Epstein forced her to have sex with, as well as new details about Epstein's relationships with Bill Clinton, Prince Andrew, and Trump.
Readers seeking support and information about suicide prevention can contact Lifeline on 13 11 14 or a local Aboriginal Health Service, Suicide Call Back Service on 1300 659 467 and Kids Helpline on 1800 55 1800 (up to age 25).
More information about mental health is available at Beyond Blue.