“I thought ‘they know what they’re doing’, they’ve got a lot riding on it and there’s a lot of evidence that it will work, so I thought I’d give it a go.”
Sydney man kicks off coronavirus vaccine trial at Oxford University
The potential vaccine has been created in just three months. It would normally take years. It’s one of several in development around the world.
More than 800 people have been recruited for the Oxford study. Half will receive the COVID-19 vaccine, while the other half will receive a control vaccine that protects against meningitis but not the coronavirus. Those taking part won’t know which they’ll receive. But they do know there’s a small risk to their health.
Dr O’Neill says he’s not concerned, nor is his wife.
“She thought it was a great idea, she was a little annoyed she couldn’t do it herself. I guess there’s always just that little niggling doubt, but she was confident that was the right thing to do.”
The team behind the trial is cautiously optimistic it will work. If it does, they hope to have a million doses ready by September, but mass manufacturing could take much longer.
“I think everyone agrees it’s the only way to get out of the lockdown, the social testing, the only way to get back to our everyday lives,” Professor Sarah Gilbert said.
The scientists will only know how effective the vaccine is if the volunteers who received the COVID-19 vaccine are exposed to the disease; they won’t be deliberately infected.
“If there's still plenty of transmission in the population who are vaccinated, we will know quite soon whether the vaccine works,” Professor Andrew Pollard said.
“But if as a result of the lockdown, there's very small numbers of cases in the months ahead, it could take some time before we have an answer."
Dr O’Neill will have to write a daily log to list any symptoms and will give blood samples at regular intervals - in addition to continuing his own work while in lockdown.
“It is strange. Right now, I’m banned from the lab, but in many ways I’m continuing doing experimentation, I just happen to be the experiment,” he said.
“It’s almost as if the weight of the world is on my shoulder. My left shoulder (where he was injected) in particular!”
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