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Manchester United vs Leicester City (Saturday 24 September, 9.30pm AEST – LIVE & FREE on SBS TV)
Both Leicester and the Red Devils enter this week’s clash in desperate need of a win as both teams already have two blemishes on their records.
United look set to shake things up ahead of the matchup, with skipper Wayne Rooney a chance to watch the game from the bench.
Liverpool vs Hull City (Sunday 25 September, 12.00am AEST)
Hull will hope to recapture the magic from their red-hot return to the Premier League, after fading following two wins to start the season.
An in-form Liverpool stands in their way, fresh off a 2-1 away win over the previously undefeated Chelsea.
Swansea vs Manchester City (Sunday 25 September, 12.00am AEST)
Manchester City will be hoping to keep its winning ways after five wins from five games to start the Premier League season.
In contrast, the Swans haven’t collected three points since their season opening win against Burnley, so they will right up against it in this week six Premier League fixture.
Bournemouth vs Everton (Sunday 25 September, 12.00am AEST)
The second-placed Toffees have a chance to grab yet another three points against the struggling Bournemouth.
With new manager Ronald Koeman seemingly having a positive effect on his squad and Romelu Lukaku back amongst the goals, Everton are well-placed to secure their spot at the top-end of the table.
Stoke City vs West Brom (Sunday 25 September, 12.00am AEST)
The good news for the Stoke faithful is that the last-placed Potters can’t sink any lower on the Premier League table. The only way is up, right? Or maybe they might just remain where they already are.
West Brom will look to string together back-to-back wins for the first time this season after the Baggies powered to a 4-2 victory over West Ham.
Sunderland vs Crystal Palace (Sunday 25 September, 12.00am AEST)
David Moyes’ men host Crystal Palace as the team continues their search for their first win of the Premier League season.
Palace will be full of confidence at the Stadium of Light following their resounding 4-1 win over Stoke last weekend.
Middlesbrough vs Tottenham (Sunday 25 September, 12.00am AEST)
Tottenham will face Middlesbrough without Harry Kane after the striker injured his ankle in Spurs’ 1-0 win over Sunderland, which begs the question: how will they cope without their star forward?
Boro has lost back to back games and will be aiming to stop that streak from being extended to three.
Arsenal vs Chelsea (Sunday 25 September, 2.30am AEST)
The pick of the round sees the Gunners host Chelsea at the Emirates. Antonio Conte’s side lost their first game of the season against Liverpool and will look to bounce back immediately.
Arsenal sit above Chelsea only on goal difference, setting up a mouth-watering clash between two Premier League heavyweights.
West Ham vs Southampton (Monday 26 September, 1.00am AEST)
West Ham enter the match off the back of consecutive 4-2 defeats at the hands of Watford and West Brom respectively.
The Saints earned their first win of the season against Swansea last week and will be weary of a Hammers’ team whose pride has taken a battering.
Burnley vs Watford (Tuesday 27 September, 5.00am AEST)
The Clarets and the Hornets round out week six of the Premier League. Watford will be riding high after their shock 3-1 victory over Manchester United.
The newly-promoted Burnley conceded three against champions, Leicester, and haven’t won since their surprise 2-0 triumph over Liverpool in round two.