Arizona clinched a bye in the first round of the NFL playoffs by beating Green Bay 38-8 on Sunday, sacking Packers quarterback Aaron Rodgers eight times and returning two of his fumbles for touchdowns.
On the penultimate Sunday of the season, other key results saw Atlanta beat Carolina to inflict a first loss of the season on the Panthers, while the New York Jets kept their playoff hopes alive with an overtime win against New England.
Arizona quarterback Carson Palmer threw for 257 yards and two touchdowns for Arizona (13-2), while Cory Redding rambled in from 36 yards with one of the fumbles for a score and Jerraud Powers took the other five yards for a TD.
Green Bay is home against Minnesota in its regular-season finale next Sunday, with the NFC North title at stake. Both teams have 10-5 records.
Carolina's bid for an undefeated season ended when Julio Jones' dramatic 70-yard touchdown reception powered Atlanta to a 20-13 victory.
Carolina (14-1) had a chance to force overtime when it got the ball with 90 seconds left and no timeouts remaining. Cam Newton completed a 19-yard pass on first down but fumbled on the following play and Adrian Clayborn recovered the ball for the Falcons, wrapping up the win.
Matt Ryan threw for 306 yards and one touchdown for the Falcons (8-7), and Devonta Freeman ran for 73 yards with a TD.
New York's Eric Decker took a 6-yard touchdown catch on the first drive of overtime - after New England chose to kick off - to give the Jets a 26-20 win against the Patriots.
Minnesota clinched a playoff berth with a 49-17 win against the New York Giants in frigid conditions.
Adrian Peterson ran for 104 yards and a touchdown over three quarters, and Harrison Smith took one of New York quarterback Eli Manning's three interceptions into the end zone.
St. Louis' Todd Gurley scored on a 2-yard TD run with 10:34 left to give the Rams a 23-17 win at Seattle, ending the Seahawks' five-game winning streak.
Pittsburgh's playoff hopes suffered a major setback with a surprising 20-17 loss at Baltimore.
Quarterback Ryan Mallet made his first appearance for the Ravens and completed 28 of 41 passes for 274 yards, including a touchdown and no interceptions.
Pittsburgh's Ben Roethlisberger threw two interceptions and was sacked three times. The Steelers will need to win at Cleveland next week if they are to make the playoffs, and rely on other results going their way.
Kansas City sealed its playoff place and recorded a team record-tying ninth straight win by beating Cleveland 17-13.
Indianapolis kept a pulse in its faint playoff hopes with an 18-12 win at Miami, with third-string quarterback Charlie Whitehurst coming off the bench to lead the Colts to two touchdown drives.
Chicago's Ka'Deem Carey caught a touchdown pass and the third-string running back also scored a touchdown on the run to help the Bears defeat Tampa Bay 26-21.
Houston took a big step toward clinching the AFC South division by winning 34-6 at Nashville, with Brandon Weeden scoring his first career rushing touchdown and throwing for two more.
Buffalo rookie Mike Gillislee ran 50 yards for a touchdown with 2:25 remaining to secure a 16-6 win for the Bills against Dallas.
New Orleans quarterback Drew Brees passed for 412 yards and three touchdowns despite his injured right foot, leading the Saints to a 38-27 win against Jacksonville.
Detroit's Matthew Stafford threw for two touchdowns, including one to Calvin Johnson early in the fourth quarter which led the Lions to a 32-17 victory over San Francisco.
