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Aussie researchers discover nasal spray that could curb obesity

Obesity

Source: AAP

More than one in four adults in Australia are obese. Globally, obesity is a major driver of chronic diseases such as cancer, cardiovascular disease, liver disease and type 2 diabetes.


Australian scientists have discovered a nasal spray that could help control appetite and burn fat, helping people to reduce weight.

Aussie researchers from Monash University have successfully tested the spray on obese mice after working out how two naturally occurring hormones -- leptin and insulin -- impact obesity.

The researchers, led by Professor Tony Tiganis, from Biomedicine Discovery Institute have shown that blocking the action of those hormones, leads to a reduction in appetite, an increase in metabolic rate and associated weight loss.

The new research released today in Cell Reports, found that elevated levels of the two enzymes responsible for controlling these hormones dampened the fat burning effects.

Tony Tiganis
Professor Tony Tiganis, from Biomedicine Discovery Institute Source: Supplied

Speaking to SBS Greek Professor Tiganis, said that obesity occurs when there is an energy imbalance.

“What we’ve done is we take advantage of the intranasal root to deliver two drugs that in enhance the response of the brain to turn naturally occurring hormones that repress feeding and increase energy expenditure”, he said.


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