Malcolm Turnbull will unveil a new ministry this week, just six months after the prime minister picked his ideal frontbench following the federal election.
The latest reshuffle is prompted by Health Minister Sussan Ley's resignation amid scrutiny of her use of expenses for travel to the Gold Coast, where she bought an apartment, and for charter flights between capital cities.
But the ministerial changes are expected to be minimal, with Fairfax and News Corp reporting Mr Turnbull may appoint Cabinet Secretary Arthur Sinodinos to the health portfolio permanently.
Senator Sinodinos has acted in the role for a week while Ms Ley stood aside.
Labor isn't holding out hope for a new minister to make changes to the coalition's health plans.
"I don't think it's going to matter who the new minister is, they have got a pretty poor agenda in health and each one of them has just been implementing what Malcolm Turnbull has been telling them to do," opposition health spokeswoman Catherine King told reporters in Ballarat.
Despite Ms Ley's resignation, the use of expenses is likely to stay in the spotlight, with new reports emerging that Finance Minister Mathias Cormann used $23,000 of taxpayer money since 2010 for trips with his wife to the Western Australia town of Broome.
The West Australian senator's office said his expenses for the trips were legitimate and appropriately declared.
