The driver, 32, has been arrested after a car ploughed into 19 pedestrians on Flinders Street.
A second man, 24, was initially arrested but police have since said he has no links to the incident.
Victoria Police are currently attending the scene of the incident between Elizabeth Street and Swanston Street.
Police officers will remain at the scene for the foreseeable future - at least until 7am tomorrow.
Police say the driver of the vehicle, was arrested by an off-duty police officer.
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