Emergency services were called to Orion Way just after 2.30am and located two males with gun-shot wounds to their legs.
A 16-year-old and 18-year-old, both from Roxburgh Park, were taken to hospital with non-life threatening injuries.
Two other men from Dallas, both aged 20, sustained facial injuries.
Police executed five search warrants this morning in Meadow Heights, Coolaroo and Craigieburn.
An 18-year-old and a 23-year-old, both from Craigieburn, were arrested, interviewed and have been released pending further enquires.
The investigation into the incident continues.
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