Burnley are all but mathematically safe from the threat of relegation that has hung over them for most of this campaign, sitting in 15th place, nine points above 18th placed Cardiff City with just three games remaining.
The Clarets put themselves in that position thanks to a battling 2-2 draw against Chelsea at Stamford Bridge on Tuesday (AEST), a performance which shows Dyche's team are capable of upsetting a big six team.
The Burnley boss is sure that Guardiola will know his team will face serious resistance at Turf Moor.
"Their approach will be of a serious nature," Dyche said.
"I don't know Pep Guardiola but I would imagine he's learned there's no walk in the park in the Premier League. There's no naivety, they won't be coming to Turf Moor expecting a walk in the park and we won't allow them that."
Burnley beat Tottenham Hotspur at home in February and drew at Old Trafford against Manchester United at the end of January while last season's clash with City in East Lancashire ended 1-1.
"We've been close with a lot of the big sides," said Dyche. "They (City) are a top side. You have to be on top of your performance levels. You need the odd bit of luck, you might need a decision but you have to focus on performance."
Although Burnley are safe, barring a remarkable series of results and a significant shift in goal difference, Dyche says they won't be relaxing just yet.
But the Burnley manager concedes they have less pressure than City, who now trail Liverpool after their 5-0 thrashing of Huddersfield Town on Saturday (AEST).
"They have the demand to win the title, while we have a different one," he said.
"That can be a weapon - you can't relax but there's a tiny bit of freedom because it is about them. We want to win and prove we can at least challenge the elite.
"The top six this season are miles in front. It's a big challenge and it's one we look forward to."
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