The 19-year-old continued his superb breakthrough season by finding the net twice in six second-half minutes to become the youngest Italian to score two goals in a Champions League match.
Porto substitute Adrian Lopez, however, quickly responded with what could prove to be a crucial away goal.
The result ended a five-match winning run in Europe for Porto, who will welcome Roma to the Estadio do Dragao for the second leg on March 7.
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