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Ronaldo has been in and out of the starting eleven under Erik ten Hag, with three goals to show from 10 starts and 16 appearances in all competitions.
Nevertheless, the 37-year-old was one of the first names Portugal coach Fernando Santos included in his 26-man squad - one that remains strong enough to contend in Qatar.
"All the players called up come with the hunger to win and make Portugal world champions, Ronaldo included," Santos said.
Portugal have been drawn in Group H and will begin their campaign against Ghana on November 25, before facing Uruguay on November 29 and Korea Republic on December 3.
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Every confirmed FIFA World Cup squad
Portugal squad
Goalkeepers: Diogo Costa (Porto), Rui Patricio (AS Roma), Jose Sa (Wolverhampton Wanderers)
Defenders: Joao Cancelo (Manchester City), Diogo Dalot (Manchester United), Ruben Dias (Manchester City), Raphael Guerreiro (Borussia Dortmund), Nuno Mendes (Paris St-Germain), Pepe (Porto), Danilo Pereira (Paris St-Germain), Antonio Silva (Benfica)
Midfielders: William Carvalho (Real Betis), Bruno Fernandes (Manchester United), Joao Mario (Benfica), Ruben Neves (Wolverhampton Wanderers), Matheus Nunes (Wolverhampton Wanderers), Otavio (Porto), Joao Palhinha (Fulham), Bernardo Silva (Manchester City), Vitinha (Paris St-Germain)
Forwards: Joao Felix (Atletico Madrid), Ricardo Horta (SC Braga), Rafael Leao (AC Milan), Goncalo Ramos (Benfica), Cristiano Ronaldo (Manchester United), Andre Silva (RB Leipzig)