Barca scrapped a 1-0 win in the fixture last season thanks to a second-half strike from Luis Suarez after Lionel Messi missed a penalty.
The Catalans were also thrashed 4-0 at San Mames in the Spanish Super Cup, the only domestic competition they failed to win last season.
Athletic only field players who were born in or brought up in the Basque Country but finished fifth in La Liga last season, missing out on Champions League football by two points and reaching the Europa League quarter-finals.
Although Barca won four of six meetings with Athletic last term, winning both legs of their King's Cup quarter-final tie as well as both league games, Luis Enrique is prepared for another testing game against Ernesto Valverde's side.
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"It is one of the most difficult games you can play away from home," Luis Enrique told a news conference on Saturday.
"The fact Athletic have a limited market to choose from, and the fact they have the same coach, means it will be the same as always.
"We are excited to play at San Mames, a stadium we love with an atmosphere you get at few other grounds in the league," the coach added.
"We'll focus on the problems Valverde will cause us, pressuring us when we're on the ball and giving us problems on the counter."
Barca lead the La Liga table on goal difference after thrashing Real Betis 6-2 in their opening game and are boosted by the return of Javier Mascherano and Marc-Andre ter Stegen from injury.
Neymar, meanwhile, has been given an extended break after helping Brazil win their first Olympic Gold medal in soccer.
Germany goalkeeper Ter Stegen will make his eighth league appearance for Barca following the departure of Claudio Bravo to Manchester City, and Luis Enrique praised the Chile international for his service to the club.
"I would like to praise the work of Claudio Bravo over the last two seasons, he did a unique and exceptional job and gave the club a lot, with performances of the highest level," he said.
"I want to highlight the attitude shown by our three goalkeepers, who recognised that the most important thing is collective success."
(Editing by Ed Osmond)
