"He will get there fine," the Spaniard told reporters. "I can give you the latest news from doctor (Ramon) Cugat in Barcelona and it's going perfectly."
Aguero, 29, has scored 21 Premier League goals for runaway champions City this season but underwent an arthroscopy in mid-April.
Argentina play their opening World Cup match against Iceland on June 16.
Guardiola said Belgium international captain Vincent Kompany and England defender John Stones were fit and ready for Sunday's league game against Huddersfield Town after earlier injury problems.
"The main target for the players is the World Cup because the Premier League is done. But the best way to arrive at the World Cup is to play good in these three games," said the manager of the final Premier League matches.
(Reporting by Alan Baldwin, editing by Toby Davis)
