"Varuzhan Sukiasyan has informed the FFA's press service about his resignation as head coach of the national team," a statement on the organisation's website (www.ffa.am) read.
The 60-year-old Sukiasyan took over in December and his second spell in charge of the side lasted just seven matches. He previously coached the side for 17 fixtures from 2000-01.
Armenia have lost all three of their qualification matches for the next World Cup in Russia and are bottom of Group E.
(Reporting By Dmitriy Rogovitskiy; Editing by John O'Brien)