"Mkhitaryan has a knee problem," Wenger told reporters. "We don't know how bad it is. He will certainly be out for Sunday."
Wenger also said goalkeeper David Ospina, who missed the CSKA match, had suffered an ankle sprain in training and would be sidelined for up to three weeks.
Petr Cech started in place of Ospina, who has been Wenger's preferred choice for European and domestic cup competitions this season.
"He just moved back on a shot and sprained his ankle. Alone, without any contact. Just a bad movement," the manager added.
(Reporting by Hardik Vyas in Bengaluru; Editing by Peter Rutherford)
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