Details about the couple's big day have not been released, but O'Loughlin's publicist confirms the Australian actor and Jones wed in Hawaii.
The news comes six months after the couple welcomed their first child together, son Lion, in October.
O'Loughlin also has a teenage son, Saxon, and Jones a four-year-old son, Spike, from previous relationships.
O'Loughlin was previously in a long-term relationship with former Neighbours star Holly Valance.
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He is best known for starring opposite Jennifer Lopez in The Back-up Plan.
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