Andrew Bogut broke his left leg less than one minute into his Cleveland debut and the Cavaliers were outgunned 106-98 by the surging Miami Heat, who have won 19 of their past 23 in the NBA.
Dion Waiters scored 29 points, Goran Dragic added 21 and the Heat held off a late rally by the Cavs.
Kyrie Irving scored 32 and LeBron James had 30 points and 17 rebounds as Cleveland dropped to 26-7 at home.
Kawhi Leonard scored 39 points, including 17 in the fourth quarter, and made big plays on both ends in the final 30 seconds as San Antonio rallied to beat Houston 112-110.
Leonard outscored James Harden 17-4 in the final quarter of a matchup between two leading MVP candidates as the Spurs won their eighth straight.
Harden finished with 39 points and 12 assists.
Andre Iguodala scored a season-high 24 points to help carry Golden State over Atlanta 119-111.
Stephen Curry had 24 points while Klay Thompson was held to 13 after a scoreless first half.
Dennis Schroder led the Hawks with 23 points - including a career-high 19 in the first quarter.
Reggie Jackson scored 24 of his 26 points in the second half and Detroit pulled away down the stretch for a 109-95 victory over Chicago.
Australian Aron Baynes has 12 points and seven rebounds for the Pistons, who climbed into a tie for the No. 7 spot in the Eastern Conference with the Bulls.
Jimmy Butler scored 27 points for Chicago.
Giannis Antetokounmpo scored 24 points, Tony Snell had a season-high 21 and Milwaukee overcame Philadelphia 112-98.
Australian guard Matthew Dellavedova added 10 points and seven assists for the Bucks while Justin Anderson tied his career high with 19 points for the 76ers.
Gordon Hayward scored 23 points and Utah led from start to finish in an 88-83 win over New Orleans.
Rudy Gobert posted his 44th double-double of the season with 15 points and 15 rebounds and Australian guard Joe Ingles had 12 points, five rebounds and four assists.
The Pelicans shot a season-low 35.7 percent with Anthony Davis contributing 20 points and 12 rebounds.
Blake Griffin scored 26 points and Chris Paul had 23 points as Los Angeles used a second-half rally to run past Boston 116-102.
Isaiah Thomas scored 32 points and handed out five assists for the Celtics.
Kemba Walker scored 28 points, Nicolas Batum added 21 and Charlotte beat Indiana 100-88.
Paul George had 36 points on 15-of-25 shooting for the Pacers.
Wilson Chandler scored a career-high 36 points and grabbed 12 rebounds, helping Denver beat Sacramento 108-96.
Darren Collison led seven Kings players in doubles figures with 17 points as they dropped their fifth straight.
Jeremy Lin scored 18 points, including nine straight in a fourth-quarter Brooklyn rally, Sean Kilpatrick added 23 and the Nets won for only the second time in 20 games with a 122-109 victory over Memphis.
Mike Conley led Memphis with 32 points and Marc Gasol added 18 as Memphis lost their third straight and fifth in the last seven.
Courtney Lee scored 20 points, Lance Thomas added 17 and New York used a big fourth quarter to rally past Orlando 113-105.
The Magic's Elfrid Payton had his first triple-double of the season with 16 points, 10 assists and 11 rebounds and Evan Fournier scored 25 points.
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