The win extended Brighton's unbeaten run to 17 games as they moved on to 51 points from 23 games to take over at the top from Newcastle who lost at home to Sheffield Wednesday on Monday.
"It is very satisfying to be top and we have earned the right to be there," said Brighton manager Chris Hughton.
"There is an awful long way to go and we need to try to play with the principles shown in the first half of the season."
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It was a sixth successive defeat for QPR who are struggling under new manager Ian Holloway.
(Writing by Ken Ferris; Editing by Louise Ireland)
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