Chelsea won last year's final at Wembley 1-0 thanks to an Eden Hazard penalty.
Giant-killers Newport County, who play in League Two (fourth tier), could face Premier League champions Manchester City if they can win their replay against Middlesbrough.
Newport, who have already knocked out top-flight Leicester City, drew 1-1 at Middlesbrough on Saturday and host the replay on Feb. 5.
News that makes sense
Your trusted source for staying up-to-date with the world around you. Get free daily news updates and analysis, straight to your inbox.
Doncaster Rovers, who play in League One (third tier) and are in the fifth round for the first time in 63 years, will host Premier League Crystal Palace.
League One AFC Wimbledon, who knocked out top-flight West Ham United, take on Championship (second-tier) Millwall, who eliminated Everton in the fourth round.
(Reporting by Simon Evans; editing by Ken Ferris)
