Chirac, 78, is one of France's most popular political figures despite becoming the first former president of the French Republic to go on trial, accused of using public money to pay people working for his party while he was mayor of Paris between 1977 and 1995.
He enjoyed immunity from prosecution as president from 1995 to 2007, but the case, which has already seen current Foreign Minister Alain Juppe convicted, has finally caught up with the avuncular former head of state.
The case could promptly grind to a halt, however, if a lawyer working for one of Chirac's co-defendants succeeds in getting a procedural matter referred upwards to France's constitutional court.
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Chirac, best known internationally for his opposition to the 2003 US-led invasion of Iraq, has denied any knowledge of corrupt payments and his lawyers accuse magistrates of harbouring a hidden political agenda.
He has been linked to a series of corruption scandals but has never been convicted. If convicted, Chirac faces up to 10 years in jail and a fine of 150,000 ($A207,200) on charges including embezzlement and breach of trust.
In the opening hearing, presiding judge Dominique Pauthe is due to deal with procedural questions. Chirac's first appearance is scheduled for the following day, when he is due to answer the judge's questions, the court said.
The hearings in Paris are the result of the merging of two separate cases - one begun by magistrates in the Paris suburb of Nanterre in 1995, and another in the capital itself dating to 1998.
The case involves seven alleged ghost jobs for which Chirac is charged with conflict of interest and 21 other jobs for which Chirac is accused of embezzlement and abuse of trust.
Nine other people are going on trial alongside Chirac, accused either of having ghost jobs or benefiting from positions as town hall employees.
Chirac denies that the people employed in the jobs were used to prepare for the 1995 presidential election, which he went on to win, insisting they were all legitimate posts in the service of Paris.
Jean-Yves La Borgne, a lawyer working for one of Chirac's former chiefs of staff, said he will argue that under the constitution the accusations in the former case can no longer be heard since they date back too far in time.
So even before Chirac's first scheduled appearance, the judge may agree to submit the question for constitutional ruling. This process would delay the trial for months.
Paris city hall last year dropped its civil charges against Chirac in return for a payment of more than 2.2 million euros ($A3.04 million) from him and the right-wing UMP party.
Chirac paid more than half a million euros of the amount from his own pocket but did not acknowledge any wrongdoing in the settlement.
Anti-corruption campaigners are still bringing separate civil charges and Chirac's lawyers are expected to raise procedural points relating to these.
State prosecutors meanwhile have called for the case to be dismissed, making it highly likely that Chirac will not be convicted.
There have been reports that Chirac's health has deteriorated - perhaps even to the point where he would be able to avoid trial.
In January his wife Bernadette denied media reports that he was suffering from Alzheimer's and insisted he would face up to his trial, though she admitted his health had declined.
A comfortable chair has been provided along with a room where Chirac can rest. The court is expected to be crowded, with over 100 media accredited.
Chirac declined to comment on the trial when questioned on Europe 1 radio on Sunday, saying only that he was "as well as can be".
