By SBS's Glenn Osborne in Melbourne
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Djokovic will start as favourite and deservedly so. He won here in 2008 and has looked in brilliant form, smashing Roger Federer in the semi-finals, even though Federer has been just about unbeatable here for the last five years.
Djokovic has also had an extra day's rest, and that could be crucial in today's 40-degree Melbourne heat.
For Murray, much more lies with him than just his first Grand Slam win at the third attempt.
As a Scot, he could be the first British man in more than 70 years to win a major if he triumphs tonight, and he may never get a better chance with Nadal and Federer out of the tournament.
Again he has proved he has the game to match the best in the world – the question is whether he has the mentality to do it on the big stage.
He confessed his first final appearance – in this tournament 12 months ago – zipped by so fast he barely remembers it. An older, wiser Murray is clearly a better player.
Murray famously reminds Djokovic that he won that first meeting as 12-year-olds, 6-0 6-1. Don't expect anything quite so one-sided tonight.
In fact, I think Britain's wait for a Grand Slam winner will take one more tournament at least.
Djokovic to win his second Australian Open in five sets.
