Steaua Bucharest’s defensive midfielder Vlad Achim, FC Astra midfielders Razvan Marin and Romario Benzar and Dinamo Bucharest striker Dorin Rotariu could make their Romania debuts after receiving call-ups from the German.
The much-travelled Daum, who replaced Anghel Iordanescu to become the second foreign coach of Romania last month, recalled VfB Stuttgart midfielder Alexandru Maxim, who missed Euro 2016 after failing to secure a regular place for his club.
There was no place in the squad for ex-captain Razvan Rat, 35, who earned his 113th cap in the 1-1 draw against Switzerland at Euro 2016.
Romania, who have not reached the World Cup finals since 1998, were drawn in World Cup qualifying Group E alongside Denmark, Poland, Armenia and Kazakhstan.
Daum faces a tough task to steer his side to Russia in 2018 after they finished bottom of their group at Euro 2016.
(Reporting by Angel Krasimirov; Editing by Brian Homewood)
