One accident occurred when a passenger bus flipped over near the resort city of Hurghada, killing 11 people and injuring 11 others, says Husam Gamil, director of emergency services for the Red Sea governorate.
Twelve people were killed and another six injured when their minibus collided with a truck carrying construction materials near Wadi Natrun, some 125km northwest of Cairo.
Both crashes happened on Sunday.
Road accidents killed some 14,400 people in Egypt last year.