Thousands of people in support of the Egyptian President Mohamed Morsi have rallied in Cairo, as rival opposition protesters rallied across the country demanding Mr Morsi's resignation.
The United States have confirmed an American was among three people killed in the coastal city of Alexandria, after political offices of the Muslim Brotherhood were torched.
The US government has warned Americans not to travel to Egypt and has told non-emergency diplomatic staff to leave, as clashes continued in the country.
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The state department also urged US nationals in Egypt "to remain alert".
Tensions have been rising ahead of a mass rally planned by the opposition on Sunday, calling Mr Morsi to step down.
A spokesman for the Muslim Brotherhood Party says the opposition's protest for a democracy is misguided.
"Well I think that even if some may think in a romantic setting that an official scenario would happen when they bring President Morsi down. The only other alternative is to live in a military dictatorship or a coup from the old regime. In all matters and scenarios it ends the political transition of Egypt into a democracy."
Several political groups say the government is dominated by the Muslim Brotherhood. The opposition also accuses Morsi of deviating from the 2011 revolution that toppled the Western-backed regime of Hosni Mubarak.
Morsi's supporters, however, say the president is cleansing Egyptian institutions of corruption. They also believe that he needs time to put into practice the principles of the 2011 revolution.
Egypt has witnessed continuing anti-government protests since Morsi took office in June 2012 in a landmark election held following the ouster of Mubarak.

