Fast bowler Toby Roland-Jones, who did not play in the first game, was retained in the 12 for the match starting at Trent Bridge on Friday.
England took a 1-0 lead in the four-match series after bowling South Africa out for 119 in their second innings, spinner Moeen Ali claiming test-best figures of 6-53 in Joe Root's first test as captain.
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(Reporting by Ed Osmond, editing by Ken Ferris)
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