Spanish media reported that Wu, the Chinese Super League's top scorer with 27 goals this season, arrived in Barcelona with a shoulder injury sustained at the Asian Cup, which could keep him out for three months.
Wu, 27, scored two goals in five games for China at the tournament, helping them reach the quarter-finals where they were eliminated by Iran.
Espanyol, owned by Chinese company Rastar Group, are 15th in La Liga and struggling for form with one win in their last 10 league games.
(Reporting by Rik Sharma, editing by Ed Osmond)
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