Indianapolis Colts owner Jim Irsay has purchased the Yellow Cloud electric guitar that Prince used in numerous concerts until the mid-1990s.
The NFL football team owner and collector of musical instruments paid $US137,500 ($A183,970) for the guitar at an auction in Beverly Hills on Saturday.
Heritage Auctions, which conducted the auction, says the solid body guitar was a favourite of the late musician from the late 1980s to the mid-1990s.
Prince died on April 21 at his Paisley Park home in Minnesota of an accidental overdose of fentanyl.
Irsay also has instruments once owned by musicians Jerry Garcia of Grateful Dead, John Lennon and Ringo Star of The Beatles and singer-songwriter Bob Dylan.
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The auction also featured other Prince-related memorabilia.

