Le Bleus have played six games - four in the Nations League - since beating Croatia 4-2 to win the 2018 World Cup but Friday's Group H opener will be their first leading to a major competition.
"It’s true that it’s not so easy to come back and to have new goals right away after winning the World Cup," Pogba told a news conference on Wednesday.
"But we have to, it’s our job. And we have to remain professional. But now we're going right into the competition, it’s the qualifiers. We want to win, we want to be the first in the group."
France were drawn with Moldova, Albania, Turkey, Andorra and Iceland, who they face at the Stade de France on Monday.
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The top two qualify for the finals, which are being staged across 12 countries.
Coach Didier Deschamps called up Kingsley Coman after the Bayern Munich forward was omitted from the World Cup squad.
The 22-year-old is determined to play at Euro 2020.
"It’s never easy, it can be easy if we make it easy," he told reporters. "We have to go into all the matches fully focused and stay motivated.
"I think the team is still hungry for trophies. But to do great things we first have to qualify."
(Reporting by Julien Pretot; Editing by Ken Ferris)
