Wales have suffered another injury blow with squad hooker Scott Baldwin ruled out for the rest of this season.
The Ospreys forward was among three hookers in Wales' Six Nations squad, with Ken Owens starting Saturday's championship opener against Scotland and Elliot Dee on the bench.
In a statement, the Welsh Rugby Union said: "Scott Baldwin has been released from Wales' NatWest 6 Nations squad due to a foot injury sustained in training.
"The injury will require surgery with a recovery time frame of at least five months.
"Scarlets hooker Ryan Elias, who made his international debut last summer, has been called into the squad."
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Wales are without several senior internationals for the Scotland clash, with Sam Warburton, Jonathan Davies, Taulupe Faletau, Dan Biggar and Rhys Webb among those sidelined.
Head coach Warren Gatland's starting line-up against Scotland includes 10 players from the in-form Scarlets, while Worcester wing Josh Adams - this season's Premiership top tryscorer - will make his Test debut.
The roof at Principality Stadium will be closed for the encounter, following earlier uncertainty.
Under Six Nations rules, both countries have to agree for the roof to be closed.
Wales' stance is always for the roof to be shut, but if Six Nations opposition disagree, then it stays open.
It is understood that Scotland expressed a preference to the Welsh Rugby Union on Tuesday for an open roof, but they also wanted an option of being able to reconsider their stance later in the week.
Wales, though, were left frustrated by the lack of a clear decision. It was set to stay open, but Scotland have now agreed to Wales' request for a closed roof.
