Gomez will play as a lone striker at the Parc des Princes with Mario Goetze returning to the left side of midfield.
Benedikt Hoewedes is replaced at right back by Joshua Kimmich with Germany needing a draw to make sure of their spot in the last 16.
Northern Ireland keep the same team who beat Ukraine 2-0 in their previous group game.
A draw will be enough for the Irish to cement a third-placed finish at least.
This would secure their passage as one of the four best third-placed finishers because they would have one more point than Group A's Albania and a better goal difference than Slovakia from Group B.
(Reporting by Patrick Vignal; Editing by Toby Davis)
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