The result leaves the United States, who had never lost to Guatemala in a World Cup qualifier, in third place at the halfway point in CONCACAF' Group C with four points, two behind Guatemala and three behind leaders Trinidad and Tobago.
The top two teams from each of the three groups go through to a final round, where three automatic berths for Russia are at stake. The fourth-placed side in the final six-team group goes to an intercontinental playoff.
(Reporting by Andrew Both in Cary, North Carolina; Editing by Peter Rutherford)
