World No.8 Tomas Berdych of the Czech Republic has pulled out of the US Open after suffering an appendicitis.
"I am very disappointed to announce I will not be able to compete at the US Open this year," the 30-year-old wrote on Twitter on Saturday.
"I was just diagnosed with Appendicitis in Cincinnati so I will be flying back to Europe for additional checks and treatment.
"I will need to take some time off to recover fully but I know I will get back as strong as ever."
Berdych, who lost in this year's Wimbledon semi-finals to eventual champion Andy Murray, pulled out of the Rio Olympic Games due to fears over the Zika virus.
The US Open starts on August 29.
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