Cavani, who injured his hamstring in February, returned for a last-minute appearance in PSG's elimination by Manchester United last week but officials said they preferred to let him recover rather than make the long trip to Asia.
Luis Suarez will make the journey and the 23-man squad contained no other major surprises with all bar Penarol full-back Giovanni Gonzalez playing their club football outside Uruguay.
The South Americans play Uzbekistan in the first semi-final of the China Cup in Nanning on March 22 and then either China or Thailand in a second game three days later.
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(Reporting by Andrew Downie, editing by Nick Mulvenney)
