Bayern Munich forward Coman injured his ankle and knee in Wednesday's training session, the FFF said in a statement.
Lemar, 20, has scored four goals in Ligue 1 from 10 appearances with Monaco this season.
France, who are level on seven points with Sweden on top of Group A, will also be hosting Ivory Coast in a friendly in Lens on Tuesday.
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(Reporting by Julien Pretot; Editing by Pritha Sarkar)
