"Rugby has been at the core of my life for the past 20 years, and it's not easy to close such an important chapter of my life," Masi, who won 95 caps, told Wasps website.(www.wasps.co.uk)
"Despite the recovery process progressing positively in the early stages, it didn't heal as hoped and it became clear I wouldn't be able to continue playing professional rugby."
Masi, who made his test debut for Italy against Spain in 1999, was part of four World Cup campaigns and made 59 appearances for Wasps in four years.
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(Reporting by Nivedita Shankar in Bengaluru; editing by Ken Ferris)
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