"This is a bad agreement that gives Iran what it wanted: the partial lifting of sanctions while maintaining an essential part of its nuclear programme," said a statement from Prime Minister Benjamin Netanyahu's office, published a few hours after the historic accord was signed in the Swiss city.
"The agreement allows Iran to continue to enrich uranium, leaves the centrifuges in place and allows it to produce fissile material for a nuclear weapon," it added.
"The accord did not lead to the dismantling of the Arak plant", the heavy water reactor being built 240 kilometres (150 miles) southwest of Tehran.
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Related: Nuclear deal is the first step for a more secure world, Obama says
"Economic pressure on Iran could have produced a much better agreement that would have led to a dismantling of Iran's nuclear capacities."
Israel's Economy Minister Naftali Bennett, the leader of a far-right party, meanwhile said his country was not bound by the Geneva deal and had a right to self-defence.
"Iran is threatening Israel and Israel has the right to defend itself," he told a military radio station.
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