Ghiraldini, who has 104 international caps, was injured in Italy's Six Nations loss to France earlier this month, and will now return to French Top 14 side Toulouse to start the recovery he hopes will put him in the frame for World Cup selection.
Ruptured knee ligaments usually take in the region of six months to heal, and with Italy set to open their World Cup campaign against Namibia on Sept. 22 in Higashiosaka, it makes Ghiraldini a doubt for the first few weeks of the tournament.
"For me a new challenge has already begun and I will face it with all the determination possible to reach the next goal, to be able to return to the highest levels and be selected for the upcoming Rugby World Cup," Ghiraldini said in a statement shortly after the injury.
(Reporting By Nick Said; Editing by Christian Radnedge)
